3-(3-PYRIDIN-2-YL-1,2,4-OXADIAZOL-5-YL)PROPANOIC ACID
3-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)-propanoic acid
CAS: 99185-87-2
Molecular Formula: C10H9N3O3
3-(3-PYRIDIN-2-YL-1,2,4-OXADIAZOL-5-YL)PROPANOIC ACID - Names and Identifiers
3-(3-PYRIDIN-2-YL-1,2,4-OXADIAZOL-5-YL)PROPANOIC ACID - Physico-chemical Properties
| Molecular Formula | C10H9N3O3 |
| Molar Mass | 219.2 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD00098188 |
3-(3-PYRIDIN-2-YL-1,2,4-OXADIAZOL-5-YL)PROPANOIC ACID - Risk and Safety
| Hazard Class | IRRITANT |
3-(3-PYRIDIN-2-YL-1,2,4-OXADIAZOL-5-YL)PROPANOIC ACID - Introduction
3-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)-propanoic acid is an organic compound with the chemical formula C11H8N4O3.
The properties of the compound are as follows:
-Appearance: White crystalline solid
-Melting point: about 160-162°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM) and methanol (MeOH)
This compound is mainly used as an intermediate in pharmaceutical research and organic synthesis. It has anti-inflammatory, anti-cancer and anti-bacterial activities.
3-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)-propanoic acid can be prepared as follows:
1. Reaction of pyridin -2-amine with malonic anhydride to give 3-pyridin-2-ylpropionic acid.
2. In the presence of sulfuryl chloride, it reacts with nicotinimide to generate 3-(3-pyridin-2-yl -1,2, 4-oxadiazol-5-yl)-propionic acid.
The following safety information is required when using and handling this compound:
-Avoid inhalation and skin contact, should wear appropriate protective equipment, such as gloves and protective glasses.
-In case of accidental contact with skin or eyes, immediately rinse with plenty of water for at least 15 minutes and seek medical help.
-It should be used in a well-ventilated place and avoid direct exposure to sunlight.
-Waste should be disposed of according to local regulations and should not be discharged at will.
The properties of the compound are as follows:
-Appearance: White crystalline solid
-Melting point: about 160-162°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM) and methanol (MeOH)
This compound is mainly used as an intermediate in pharmaceutical research and organic synthesis. It has anti-inflammatory, anti-cancer and anti-bacterial activities.
3-(3-Pyridin-2-yl-1,2,4-oxadiazol-5-yl)-propanoic acid can be prepared as follows:
1. Reaction of pyridin -2-amine with malonic anhydride to give 3-pyridin-2-ylpropionic acid.
2. In the presence of sulfuryl chloride, it reacts with nicotinimide to generate 3-(3-pyridin-2-yl -1,2, 4-oxadiazol-5-yl)-propionic acid.
The following safety information is required when using and handling this compound:
-Avoid inhalation and skin contact, should wear appropriate protective equipment, such as gloves and protective glasses.
-In case of accidental contact with skin or eyes, immediately rinse with plenty of water for at least 15 minutes and seek medical help.
-It should be used in a well-ventilated place and avoid direct exposure to sunlight.
-Waste should be disposed of according to local regulations and should not be discharged at will.
Last Update：2024-04-09 19:06:02
